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Way To Cure Premature Ejaculation
Aspray touted as the first potential treatment for premature ejaculation has proved effective in a second study, according to the company that developed it.
PSD502 -- which combines the drugs lidocaine and prilocaine -- is sprayed on the head of the penis before intercourse.
The study of men in Canada, Poland and the United States found that those treated with the spray five minutes before intercourse were able to delay ejaculation up to five times longer than those who used a placebo.
In addition, men who used the spray and their partners reported improved sexual satisfaction.
The findings, presented recently at the annual meeting of the Sexual Medicine Society of North America, are consistent with those from a previous trial in Europe, according to San Diego-based Sciele Pharma Inc.
"Premature ejaculation can have a powerful negative impact on the emotional and sexual lives of men and their partners," Professor Stanley E. Althof, of the Center for Marital and Sexual Health of South Florida, said in a news release.
"Recently, the international sexual health community agreed that PE [premature ejaculation] should be defined as ejaculation occurring within approximately one minute of penetration that causes the patient distress.
Now we need to work to develop treatments, and these encouraging results with PSD502 seem to be a step in the right direction."
Sciele Pharma plans to seek U.S. Food and Drug Administration approval of the spray.
Premature ejaculation affects about one-third of U.S. men aged 18 to 59, which means it's twice as common as erectile dysfunction. No prescription treatments are approved in the United States to treat PE.
Source: HealthDay News
Image: Spray Can by artist Roy Lichtenstein
Published Nov 21 2009
Source: The Daily Chilli
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Woman Does Have Viagra?
The drug flibanserin, originally created as an antidepressant, is effective in treating women with low libido, pooled results from three separate clinical trials have found.
The trials were the first ever to test a therapy that works at the level of the brain to enhance libido in women reporting low sexual desire, said Dr John M. Thorp Jr, professor of obstetrics and gynecology at the University of North Carolina and the principal investigator for North America in the studies.
"Flibanserin was a poor antidepressant," Thorp said. "However, astute observers noted that it increased libido in laboratory animals and human subjects."
"So, we conducted multiple clinical trials and the women in our studies who took it for hypoactive sexual desire disorder reported significant improvements in sexual desire and satisfactory sexual experiences.
"It's essentially a Viagra-like drug for women in that diminished desire or libido is the most common feminine sexual problem, like erectile dysfunction is in men," Thorp was quoted as saying bySciencedaily.com
Studies have shown that the prevalence of hypoactive sexual desire disorder in the US ranges from 9 percent to 26 percent of women, depending on age and menopausal status.
Flibanserin is currently an investigational drug and is available only to women taking part in clinical trials.
The results were reported on Nov. 16, at the Congress of the European Society for Sexual Medicine in Lyon, France.
The presentation was given by Dr Elaine E. Jolly, the overall principal investigator and a professor at the University of Ottawa in Canada.
Jolly, Thorp and colleagues pooled data from four clinical trials of flibanserin conducted in the U.S., Canada and Europe.
A total of 1,946 pre-menopausal women ages 18 and older were randomized to receive either flibanserin or placebo for 24 weeks, with 4 weeks of pre-treatment baseline measurement and 4 weeks of post-treatment follow-up.
The researchers concluded that treatment with 100 milligrams of flibanserin once a day was associated with significant improvements versus placebo in the number of satisfying sexual events (SSE) reported, sexual desire, a reduction in distress associated with sexual dysfunction, and sexual functioning as measured by FSFI.
"These results point to a novel approach to pharmacologic treatment of the sexual problem that plagues reproductive age women the most, and may over time prove to be an effective treatment without the side effects of androgen replacement therapy, which is the only treatment currently available," Thorp said.
The trials were funded by Boehringer Ingelheim Pharmaceuticals, the manufacturer of flibanserin.
- sciencedaily.com
Published Nov 20 2009
Source: The Daily Chilli



